| Top News:  The gross public debt of the United States reached 40.047 trillion dollars on Tuesday, according to data released by the Treasury Department. It is the first time the figure has crossed that threshold, and it has arrived earlier than expected: the Congressional Budget Office had projected 39.4 trillion by the end of fiscal 2026 and placed the jump to 40 trillion in 2027.
 Federal judge Ernesto Kreplak, sitting in La Plata, this week admitted a class action and requested urgent reports from the Ministry of Economy, the National Roads Directorate and Banco Nación on the use of resources from the Integrated Road System (SisVial), a trust fund financed by the tax on liquid fuels whose legal purpose is the construction and maintenance of national highways.
 The Duke and Duchess of Sussex, Prince Harry and Meghan Markle, will settle in the United Kingdom from this autumn, though they will not resume their roles as working members of the royal family, British media reported on Wednesday. The story was broken by The Telegraph and corroborated to the Associated Press by a person close to the couple who was not authorised to speak publicly. There has been no official statement from the palace or the Sussexes.
 Argentina's Large Investment Incentive Regime (RIGI), created in 2024, "consolidated a strongly extractive profile and did not stimulate new sectors," according to a report released on Wednesday by the RIGI Observatory, a coalition of civil society organisations and academic centres that examines the scheme from a critical standpoint.
 Pharmaceutical companies Merck, known as MSD outside the United States and Canada, and Moderna announced on Wednesday that their individualized neoantigen therapy, intismeran autogene, met its endpoints in a phase 3 trial in melanoma patients. It is the first positive result at that stage for an mRNA-based cancer treatment.
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